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Real-world evidence (RWE) is at the heart of value-based care, health equity, regulatory compliance, and impactful medical research.

Circles harness the power of RWE to create proprietary and statistically significant datasets in the context of any medical specialty, and representing value to all healthcare constituencies.  

In the Select Client Activities section of this newsletter, we summarize recently launched Real-World Evidence Programs.  In the Select Company Activities section, we highlight several major use case categories.

Please contact us to discuss how Real-World Evidence Programs can advance your clinical, scientific, and commercial objectives.

Select Client Activities

ROSM Real-World Evidence Program

With eight locations in the Washington D.C. area, ROSM is one of the largest non-surgical orthopedic practices in the country.  

ROSM has always selected its diverse protocols in an evidence-based manner.  It will now broaden that effort by applying focused, real-world evidence strategies against every ROSM clinical intervention.

By deploying no fewer than seven Circles, ROSM will own, and generate sustainable value from, many rich, statistically significant, and tightly integrated datasets.

Dr. Imran Siddiqui, Director of Clinical Operations at ROSM, says:

“RegenMed shared our strategic vision, and with its turnkey platforms and deep regenerative medicine experience, was the natural partner to help us design and expand this broad initiative.”

For more information, including how to join ROSM’s Circles, see here.

EmCyte™ Real-World Evidence Program

EmCyte Corporation is a world leader in the design, manufacture, and distribution of integrated systems for platelet rich plasma, bone marrow cell concentrate, adipose concentrate, bone marrow harvesting, and PRP analysis.  

EmCyte also supports Gulf Coast Biologics, led by Peter A. Everts, PhD, FRSM.  GCB is a separate entity dedicated to the education and training of doctors from around the world in the evidence-based clinical use of biologics-based therapies.

EmCyte and GCB have long been using the Circles platform to develop clinically and statistically significant datasets supporting various biologics treatments for knee and shoulder pathologies. (These have included patients presenting with bi-lateral conditions.)

Dr. Everts says:

“We partnered with RegenMed over a year ago to collect real-world data by using RegenMed’s Circles Program in order to collect data that can be used to provide evidence, more than trends only.

Our goal is ultimately to have clear cut evidence what optimal preparation methods and protocols are to facilitate physicians in optimizing their treatment strategies, using a variety of highly efficient and reproducible protocols.”

The platform has accommodated our highly specific research objectives, customer engagement and feedback has been overwhelmingly positive, and we have already generated valuable, statistically significant data for up to 1 year, clearly leading us to further refinement of our protocols.”

For more information on the EmCyte and Gulf Coast Biologics Real World Evidence Program, see here.

Summus Medical Laser Real-World Evidence Program

Summus Medical Laser® has partnered with RegenMed to establish a comprehensive Real-World Evidence Program.  The program will support thousands of providers around the world by developing and sharing best practices for improving patient recovery and care.  

The RWE Program will expand Summus Laser's Class IV Laser Therapy research to generate validated and statistically significant datasets that will be used to enhance patient care, outcomes, and to further product innovations.

Pete Cousins, the COO of Summus Medical Laser, says:

"We look forward to unlocking new frontiers of innovation and patient care through the RWE Program.  
Collaborating with RegenMed presents an invaluable opportunity to accelerate and push the limits of laser therapy and its capabilities, ultimately advancing medical science and enhancing patient outcomes."

For more information, including how to join the Summus Medical Laser Circles, see here.

Breakthrough Regenerative Orthopedics Launches SI Joint Circle

Timothy Mazzola, M.D practices non-operative orthopedic medicine at Breakthrough Regenerative Orthopedics.  For patients presenting with pain and dysfunction in the lower back, hip, and knee regions, he focuses on instability of the sacroiliac (SI) ligament and its myofascial attachments.

Dr. Mazzola’s Circle will evaluate the efficacy of ultrasound guided PRP and MFAT injections for such patients.  Baseline and longitudinal outcomes measures will incorporate his proprietary physical examination measurement, “Millimeters of Motion,” to quantify SI ligamentous laxity.  

Dr. Mazzola says:

“Breakthrough Regenerative Orthopedics is proud to partner with RegenMed to collect real world evidence on treating SI dysfunction and ligamentous laxity.
RegenMed has become our go-to partner for clinical data collection based on their commitment to user-friendly, customer-focused data collection solutions for busy clinicians like ourselves.”

Dr. Mazzola will also be delivering the keynote address at the upcoming C3 Annual Summit: Treatment Strategies for Lumbopelvic Pain and Dysfunction.

More details on Dr. Mazzola’s Circle, as well as the opportunity to participate, can be found here.

ISNS Launches Consumer-Facing Real-World Evidence Program For Nutraceuticals

The International Science and Nutrition Society is an international organization comprising physicians, scientists, and other experts in complementary and integrative medicine.  Its advances science-based knowledge in nutrition, nutraceuticals, phytology, and ecology.  

ISNS works closely with RootBrands in preparing and distributing nutraceuticals and other health/wellness products throughout North America and Europe.

ISNS and RootBrands have launched a Real-World Evidence Program to track long-term outcomes against customer reported baselines.  The Circles design and data analyses will involve ISNS clinicians and scientists.  Outcomes assessments include BMI, SF-12 Mental, SF-36 Emotional, SF-12 Physical, and SF-36 Energy/Fatigue.

For more information on the ISNS Circles, see here.

Select Company Activities

Co-Marketing Programs

Circles create proprietary and statistically significant datasets representing value to all healthcare constituencies.  Categories of value include clinical decision-making, product development, regulatory approvals, monetization, competitive differentiation, and patient and HCP engagement.

Circles Co-Marketing Programs accelerate that value for both provider and industry Clients.  Program elements include:

• Regular Client Reports
• Circle Academies
• Circle Member Recruitment
• Publication
• Continuity of Care
• Third-Party Support
• Dataset Monetization

To find out more about Circles Co-Marketing Programs, see here.

Types of Real-World Evidence Programs

Real-World Evidence Programs deliver clinical, scientific, and financial value for all healthcare constituencies.  Recent articles published by RegenMed and covering various use cases include:

• ‍CREATING LICENSABLE REAL-WORLD EVIDENCE DATASETS
• ‍CIRCLES FOR OTC PRODUCT MANUFACTURERS
• ‍CIRCLES FOR INDEPENDENT PROVIDER GROUPS
• ‍CIRCLES FOR SUSTAINED MENTORING BY CLINICAL LEADERS
• ‍REAL-WORLD EVIDENCE PROGRAMS FOR ACADEMIC MEDICAL INSTITUTIONS
• ‍REDISCOVERING AND RE-IMAGINING MEDICAL RESEARCH
• ‍CIRCLES FOR ASSESSMENT OF COGNITIVE IMPAIRMENT

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